Searchable abstracts of presentations at key conferences in endocrinology

ea0016p354 | Growth and development | ECE2008

Potential ageing effects in long-term cultured mouse neurospheres

Vukicevic Vladimir , Gebauer Linda , Jauch Anna , Ziegler Christian , Krug Alexander , Chung Kuei-Fang , Funk Richard , Bornstein Stefan , Mueller Albrecht , Ehrhart-Bornstein Monika

Neural cells are isolated from forebrain of 14.5 days old mouse embryos. In selective conditions these cells cluster forming sphere-like structures – neurospheres (NSCs). NSCs are heterogeneous structures containing only 2–5% of stem cells and progenitors being reportedly capable to transdifferentiate. Initially, aim of this study is to establish optimal culture conditions prior to investigation of transdifferentiation capacity of transplanted NSCs in kidney and adre...